Abstract：The selectable marker genes such as antibiotic and herbicide resistant were used to select the transgenic plants in most plant genetic transformation．But these resistant marker genes could cause potential hazards in human health and ecological environment security．There are 2 methods available to get marker-free transgenic plant now．One is using the safe marker，the other is removing the resistant marker gene after selection．This paper expounds the recent research progress about the on-using safe marker gene and technique of eliminating resistant marker gene and their application in vegetable crops．It also briefly analyzes the advantages and disadvantages of these 2 methods and prospects their future development．
