Abstract:Six generations(P1,P2,F1,F2,BC1P1 and BC2P2)derived from a cross of 200932(orange flesh)and 200930(green flesh)were used to study the inheritance of melon(Cucumis melo L.)β-carotene content traits by joint analysis method of multiple generations.The results showed that β-carotene content fitted 2 pairs of additive-dominance-epitasis major genes plus additive-dominant polygene model(E-1).The major gene heritability of F2 population was 92.66%,the polygene heritability was 5.40%,The major gene heritability of BC1P1 population was 86.80%,the polygene heritability was 0.The major gene heritability of BC2P2 population was 59.88%,The polygene heritability was 38.60%.