Abstract: FLOWERING LOCUS C(FLC)is a key deciding factor in regulating plant bolting and flowering network.Along with the development of epigenetics,scientists found that histone modification and other epigenetic regulation of FLC expression played very important role in regulating plant bolting and flowering.Chromatin covalent modification included acetylation and methylation of lysine and arginine.The recent characterization of FLC repressors and activators has shown that some of these regulatory proteins are involved in the covalent modification of FLC chromatin and controlling the flowering time.This paper reviewed the present internal and external status on studying the regulating gene FLC for plant bolting and flowering,and epigenetic regulation and its expression.The paper also provided direction and focus for future studies according the prob lems existing in present research.