Taking pepper variety‘ Haonong No.11’ F1hybrid as experimental material，this paper carried out field trial in He county of Anhui Province，and studied on the nutrients absorption and distribution rule of autumn-winter pepper in greenhouse under mulched drop-irrigation system．The results indicated that the pepper yield reached 47 100 kg·hm-2，the total accumulation of dry matter was 8 163 kg·hm-2，and the harvest index was 0.70．The most rapid dry matter increasing period for plant was at the stage of fruit formation．Its accumulation quantity accounted for 33.3% of the whole growth period．Pepper nutrient absorption during the entire growth period is potash（ K）＞ nitrogen（ N）＞ phosphorus（ P），and the absorption of N，P2O5 and K2O were 186、61.0、313 kg·hm-2，respectively．The absorbent N，P，and K were mainly distributed to fruits，and their harvest indexes were 0.59，0.78，0.58，respectively．The N，P，and K absorptive amount were the highest in the stage of fruit formation，accounting for 37.6%，28.5%，38.4%，respectively．As for the Ca，Mg，B，their absorptive amount was Ca ＞ Mg ＞ B．The plant absorbed CaO，MgO and B were 135、74.9、0.13kg·hm-2，respectively，and the harvest indexes were 0.08，0.32，0.46，respectively．The highest Ca and Mg accumulation were in leaves，accounting for 79.8% and 54.1%，respectively．B was mainly distributed in fruits and leaves accounting for 46.2%，39.2%，respectively．The Ca，Mg and B absorptive amounts were the highest during the stage of fruit formation accounting for 34.6%，33.3%，38.2% of the whole growth period．