Abstract：Six generations（P1，P2，F1，F2，BC1P1 and BC2P2）derived from a cross of 200932（orange flesh）and 200930（green flesh）were used to study the inheritance of melon（Cucumis melo L.）β-carotene content traits by joint analysis method of multiple generations．The results showed that β-carotene content fitted 2 pairs of additive-dominance-epitasis major genes plus additive-dominant polygene model（E-1）．The major gene heritability of F2 population was 92.66%，the polygene heritability was 5.40%，The major gene heritability of BC1P1 population was 86.80%，the polygene heritability was 0．The major gene heritability of BC2P2 population was 59.88%，The polygene heritability was 38.60%.
