关键词: 溴氰虫酰胺, 吡蚜酮, 南瓜, 残留消解, 安全间隔期

Abstract: This paper developed an analytical method for detection of cyantraniliprole and pymetrozine
residues in pumpkin，and studied the digestion dynamic rule and final residues of cyantraniliprole·pymetrozine
water dispersible granules in pumpkin from Hebei and Zhejiang Provinces．The samples were extracted
with acetonitrile，purified by N-propyl ethylenediamine（PSA）and determined by liquid chromatography
tandem mass spectrometry．The results showed that the limit of quantification（ LOQ） of cyantraniliprole
and pymetrozine in pumpkin samples were 0.01 mg · kg^-1 and 0.005 mg · kg^-1．The addition recovery
rate of cyantraniliprole in the range of 0.01-1.0 mg · kg^-1 was 100%-104%．The addition recovery rate of
pymetrozine in the range of 0.005-0.5 mg·kg^-1 was 96%-107%．The residue digestion rules of cyantraniliprole
and pymetrozine in pumpkin were all conformed to the first-order kinetics process．The final residue of
cyantraniliprole in pumpkin was ≤ 0.031 mg · kg^-1，and the final residue of pymetrozine was ≤ 0.023 mg ·
kg^-1．The recommended dosage by enterprise was 450 and 675 g·hm^-2，and the safe interval was 14 days．
Pumpkin fruits during harvesting period were safe to eat．

Key words: cyantraniliprole, pymetrozine, pumpkin, residue digestion, safe interval